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endpoints granulation tissue formation, collagen organization, egr-1 expression Reported finding PL 14736, the Pliva development designation for this peptide, was reported as more active than PDGF-BB in stimulating early collagen organization, and up-regulated egr-1 gene expression with associated downstream pathways

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Chronic inflammatory bowel diseases such as Crohn’s Disease affect the ileum and impair B12 absorption